Effects of Muscle Strength Training Associated with Blood Flow Restriction on the Functional Capacity of People with Stage 3 Chronic Kidney Disease

Abstract

Introduction: This study investigated the effects of muscle strength training associated with blood flow restriction (BFR) on the functional capacity of individuals with stage 3 chronic kidney disease (CKD-3). Methods: Randomized clinical trial with 40 participants of both sexes, aged between 35 and 75 years. Participants were divided into four groups: control, low-load strength training, high-load strength training, and low-load strength training combined with BFR. The protocol lasted 12 weeks, with three weekly sessions of muscle strength exercises. The variables analyzed included muscle strength, flexibility, agility, walking speed, cardiorespiratory fitness, and physical activity level (IPAQ). Results: The RFS group showed the greatest gains in upper and lower limb strength, flexibility, cardiorespiratory fitness, and walking speed, with statistical significance (p<0.05) and high effect sizes. In addition, there was a significant improvement in all 10RM test exercises. Conclusion: Strength training associated with RFS is an effective and safe strategy for improving the functional capacity of people with CKD-3, promoting gains comparable to those obtained with high loads.