Estudo de Imunoterapias com Foco em Vacinas para Doença de Parkinson: uma prospecção científica e tecnológica
DOI:
https://doi.org/10.9771/cp.v19i2.65190Palavras-chave:
Doenças Neurodegenerativas, Terapêutica, Vacina.Resumo
A Doença de Parkinson (DP) é uma doença neurodegenerativa caracterizada pela perda de neurônios dopaminérgicos, com grande impacto na qualidade de vida dos pacientes. Este estudo investigou o desenvolvimento de imunoterapias baseadas em vacinas para a doença, utilizando as bases de dados ScienceDirect e PubMed para prospecção científica e WIPO, Google Patents e INPI para prospecção tecnológica. Na prospecção científica, foram identificados quatro anticorpos monoclonais e duas tecnologias imunoterapêuticas em fase clínica. Na prospecção tecnológica, os EUA e o Japão lideram com maior número de patentes ativas. No Brasil, não foram encontradas publicações ou patentes relacionadas. Das bases WIPO e Google Patents, apenas seis patentes relevantes foram localizadas. Os resultados destacam a necessidade de estratégias inovadoras, como a análise de genes, de proteínas e de células imunológicas para desenvolver imunoterapias eficazes e seguras, reforçando a importância da pesquisa científica e tecnológica no avanço das terapias contra a Doença de Parkinson.
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